Clinical management of autoimmune hepatitis

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Clinical features and management of autoimmune hepatitis.

Autoimmune hepatitis (AIH) is a chronic hepatitis of unknown etiology which can progress to cirrhosis. Its clinical manifestations are highly variable and sometimes follow a fluctuating course. Diagnosis is based on characteristic histologic, clinical, biochemical and serological findings. Anti-inflammatory/immunosuppressive treatment frequently induces remission but long-term maintenance thera...

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Autoimmune hepatitis

Autoimmune hepatitis is (AIH) is a chronic hepatitis that occurs in children and adults of all ages. It is characterized by immunologic and autoimmune features, including circulating auto antibodies and high serum globulin concentrations. It was first described in the 1950s by term of chronic active hepatitis. It has 2 types with different auto antibodies. Diagnosis is based upon serologic and ...

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Expert clinical management of autoimmune hepatitis in the real world.

BACKGROUND High-quality data on the management of autoimmune hepatitis (AIH) are scarce. Despite published guidelines, management of AIH is still expert based rather than evidence based. AIM To survey expert hepatologists, asking each to describe their practices in the management of patients with AIH. METHODS A survey questionnaire was distributed to members of the International AIH Group. ...

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Autoimmune hepatitis: clinical challenges.

Waldenström first described the disease entity now termed autoimmune hepatitis (AIH) in 1950, when he observed a chronic form of hepatitis in young women.1 This hepatitis led to cirrhosis and was associated with jaundice, elevated gamma globulins, and amenorrhea.2 The disease was found to be associated with other autoimmune syndromes3 and was later termed “lupoid hepatitis” because of the prese...

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Autoimmune hepatitis (AIH) is a complex autoimmune disease characterized by immune-mediated destruction of hepatic parenchyma which can result in cirrhosis, liver failure, and death. Current American Association for the Study of Liver Diseases (AASLD) and European Association for the Study of Liver (EASL) guidelines recommend corticosteroids alone or in combination with azathioprine as first-li...

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ژورنال

عنوان ژورنال: United European Gastroenterology Journal

سال: 2019

ISSN: 2050-6406,2050-6414

DOI: 10.1177/2050640619872408